ChemCom has identified multiple hORs activating by the most important Key Malodorant Compounds (KMMs)…
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Relying on its experienced scientific team, its unique scientific excellence, and its patented technology, ChemCom provides a wide range of services in the field of sensory communication mediated by olfactory and taste receptors.
• Identify agonist for key ORs involved in malodor perception
• Validate these antagonists as odor blockers with a human panel
• Deliver a blocking agent to be incorporated into the client’s final product
• Identify Enhancers / Positive Allosteric Modulators (PAMs) for targeting ORs
• Validate these enhancers / PAMs as boosters of the target odor perception with a human panel
• Deliver a stimulating agent to be incorporated into the client’s final product.
• Identify ORs that respond to the odorant compound of interest
• Screen libraries to find alternative activators of the identified ORs
• Use our large databases that link together compounds / hORs / organoleptic properties / physical and chemical parameters
• Deliver compounds that can replace the initial molecule of interest
• Profiling of molecules or blends on the whole OR library
• Screening for similarities of hORs activation patterns and formulations
• Elimination of redundant material
• Deliver a simplified blend that has the same organoleptic properties as the original one
• Implement a running animal OR screening platform (short timeframe) using our genetic expertise and network
• Identify ORs for compounds or blends of interest
• Identify either antagonists, enhancers or alternative agonists
• Deliver odor blockers, odor enhancers, new odorants, or blends for the selected animal
ChemCom has identified multiple hORs activating by the most important Key Malodorant Compounds (KMMs)…
Our main research activities are focussing on the deorphanization of hORs and the identification of agonists, antagonists or enhancers for these hORs…